DefenAge Promo Codes and Coupons September 2025

BEAUTY SLEEP DUO

Wake up with healthier, fuller-looking hair using DefenAge’s Beauty Sleep Duo...

MENS SKIN BOOSTER

Men's Skin Booster Kit Details Men’s Skin Booster is a juiced-up version of the Men’s Skin Provision system. We recommend using the Booster once or twice a year to jumpstart the skin for high-performance and following with the Provision kit for skin maintenance until the next boost. The Booster is a complete, professional-grade, annual skin detailing service tailored to men’s need. The Men’s Skin Booster concept was developed after multi-year clinical studies and observations proved that the extra dose of Defensin-molecules “boosts” skin to repopulate with fresh, new, and young cells when done at least annually. This combination produces outstanding benefits for the look and appearance of the skin and overall visible skin health. The Booster kit is designed to work up to 6 weeks. During the first, “boosting” 2-3 weeks, we will ask you to use all 4 products found in the kit, and then complete the rest of the time with daily cleanser and moisturizer. What The Men's Skin Booster Does •  Jump starts the health of the skin to look fresh, energized, and young. •  Provides a complete service for the skin. •  Optimizes skin regeneration and cell turnover. •  Boosts skin clarity. •  Repairs the skin moisturization system and fills the skin up to its natural hydration level. •  Optimizes the natural healing cycle and calms signs of inflammation. •  Normalizes signs of visible redness. •  Boosts healthy skin immunity. •  Reduces the appearance of pores and wrinkles. •  Boosts the appearance of skin tone, smoothness, and texture. •  Initiates the pore-cleaning cycle. •  Provides deep cleaning of the skin and removes surface debris, air pollutants, oils, soap residuals, and sweat build-ups. •  Polishes the skin surface and fades skin imperfections. •  Corrects visible signs of skin exhaustion, damage, and aging on a global scale. Why The Men's Skin Booster Is Different •  Provides a professional-grade skin detailing service and initiates regenerative renewal. •  Contains the highest-possible (boosting) concentration of Defensin-molecules, proven in natural skin renewal power. •  Backed by US Patent No. 11,491,096, nineteen clinical studies, and advanced regenerative-medicine and dermatology research. •  Enables instant results. •  Perfect for skin restorative treatment. •  Effective for all skin types and all stages of skin aging. •  Non-irritating and gentle on sensitive skin. •  Evolved from DefenAge’s first generation of products for men, the Men’s Kit. The Men's Skin Booster Kit Contains: •  Anti-Aging Concentrate | 8-in-1 BioSerum | 0.33 fl. oz. •  Innovative Moisturizer | 24/7 Barrier Balance Cream - Men's Formula | 1.5 fl. oz. •  Face Cleanser | 1-Step Multi-Cleanse | Net Wt. 5 oz. •  Skin Polisher | 2-Minute Reveal | Net Wt. 0.75 oz. Made in the U.S.A. DefenAge's Men's Kit is “ideal for the man who wants to look his best with an easy-to-use, all-in-one regimen,” - Dermatologist Jared Jagdeo, MD, New York. Dr. Jagdeo recommends the Men's Kit as a “comprehensive kit that addresses most skin concerns.” Source: NBCnews.com Best 17 Skincare Products For Dark Skin, According To Dermatologists "I'm a male in my 30's who has never paid much attention to skincare outside of a face wash when i shower. I live in the midwest so our season/weather is constantly changing and it's finally caught up to me. I was having dry skin issues around my nose, under my beard and above my eyes so I began looking into my options as far as lotions and a new wash. A good friend who pays way more attention to these things told me about the DefenAge Men's Kit. The bag is nice for travel, the directions were easy to follow and I noticed results pretty quickly. First of all - I have had an irrational fear of lotion on my face for much of my adult life - but the balance cream is light and it settles nicely after application. After a few minutes I forgot I had put lotion on at all. I hadn't even heard of BioSerum before but it really left me feeling fresh and confident that my dry skin would not be an issue when i stepped out the door to go to work or hangout for friends. I feel pretty dumb for just getting into this world. Ive totally replaced my other face wash and now have a quick routine every night after I shower. I don't ever leave reviews on products unless they really impress me and this kit really did." - David D. Source: Google Reviews ► Press Release DefenAge® Skincare Announces Men’s Skin Provision System Specifically Formulated for Men Carlsbad, CA – November 9, 2022 – DefenAge® Skincare, manufacturer and distributor of the revolutionary, evidence-based, anti-aging products, launches its first skincare system developed for men. Evolved from the DefenAge Men’s Skincare Kit, the brand’s highly successful and popular skincare set for men, the new Men’s Skin Provision is further tailored directly to men’s unique needs and expectations for skincare products.Read more ►

CLINICAL POWER TRIO

8-IN-1 BIOSERUM

The 8-in-1 BioSerum is DefenAge's iconic bestseller. This patented technology, remarkably smart bio serum formula seems to understand your skin’s needs better than your DNA. Designed to activate, orchestrate, and energize the skin, this biologically advanced, anti-aging, and cream-like serum concentrate provides an unprecedented concentration of defensin molecules contained in the Age-Repair Defensin® Complex. Dermatologists and aesthetic professionals name defensins as a perfect retinol alternative and the 8-in-1 BioSerum as a retinol or bakuchiol serum replacement. The best part? Results are equal to eight separate serums. Get your best skin ever with 8-in-1 BioSerum. The 8-in-1 BioSerum is perfect as a stand alone skincare product. The 8-in-1 BioSerum is also well known as a "treatment multiplier," dermatologists recommend the 8-in-1 BioSerum for pre- and post- aesthetic procedures to amplify the results of microneedling, RF-microneedling, fractional and ablative laser, and Sofwave. Find more about expected results when you add the 8-in-1 BioSerum to your treatment at the Clinical Studies tab. Read expert opinions here.     How Our Bio Serum Works   The DefenAge 8-in-1 BioSerum works by improving the overall health and appearance of the skin. It helps   •  Rejuvenates smoothness. Improves overall visible skin health and quality. •  Minimizes the look of fine lines, wrinkles, pores, and skin pigmentation and discolorations. •  Promotes radiance and revives the skin’s natural moisture for an ultimate glow. •  Brightens the overall skin tone and clarity and enhances skin luminosity. •  Renews the feeling of skin firmness, elasticity, and texture. •  Helps improve the appearance of skin redness. •  Promotes the skin barrier and skin immunity.     Why 8-in-1 BioSerum Is Different   Our bio serum is an excellent retinol and bakuchiol serum alternative. We’ve combined advanced, targeted treatment with established and validated science to bring you a skin care product that is unlike any other on the market. Here’s what makes 8-in-1 BioSerum different.   •  Contains five times more defensin molecules than any other formula. •  Light-weight application; “you don't feel it when you're wearing it”. •  Effective and safe for the entire face, including the delicate skin around the eyes and lips, and the neck and décolleté. •  High-performing on crepey thin skin on the neck and arms. •  Fast-acting anti-aging — first results are seen within a few weeks. •  Perfect as a daily skin care product for both men and women. •  Effective for all stages of skin aging, including for people above 70. •  Non-irritating and gentle on sensitive skin, unlike retinol. •  Tolerated by all skin types, including those with rosacea and melasma. •  Highly effective for pre- and post- aesthetic procedures to achieve the optimal outcomes, including microneedling and fractional and resurfacing laser treatments. Primes the skin to a quick and robust response. Optimizes healing and minimizes the risk of acne break-outs post-procedure. •  Effective in preparing skin before fillers — start using four to six weeks before procedures. •  DefenAge's most “likable” product with the most impressive consumer feedback.   Made in the U.S.A.     Add These Moisturizers to Your BioSerum Routine:   {{widget type="WeltPixel\OwlCarouselSlider\Block\Slider\Custom" slider_id="2"}}     Ten Specific Ways Leading Dermatologists Recommend Using the 8-in-1 BioSerum:   For daily use. It’s lightweight. “You can’t even feel it when you’re wearing it.” Dermatologist Vivian Bucay, MD   For sensitive skin. It delivers anti-aging results but it’s “not irritating like a retinol or acids.” Dermatologist Anne Chapas, MD   For older age. Even old skin has young dormant cells that can be turned on by defensins. “We saw a marked difference at 2 months” in a 73-year-old patient. Dermatologist Angela Bowers, MD   For better skin quality, including firmer skin, fewer fine lines, more luminosity and clarity, and a reduced appearance of pores. Dermatologist Anne Chapas, MD   After microneedling, patients are “less likely to break out with acne post treatment.” Dermatologist Vivian Bucay, MD   “4 to 6 weeks before having filler procedures” to prep the skin and enhance results. Dermatologist Kathleen Welsh, MD   Before and after ablative skin treatments, which “primes skin to respond more quickly and robustly, healing faster.” Dermatologist Steven Swengel, MD   To target specific areas, including around the eyes and lips. Dermatologist Angela Bowers, MD   Beyond the face: on the neck and décolleté. Dermatologist Steven Swengel, MD   For crepey thin skin on the neck and arms. Dermatologist Kathleen Welsh, MD   REFERENCE:Dermatologists weigh in on DefenAge’s 8-in-1 BioSerum: Patient outcomes, optimal use. The Dermatology Digest (2021) January, p. 40-42.     How and Why You Should Add the 8-in-1 BioSerum to Your Skincare Regimen?   Dermatologists agree, if you do one nice thing for your skin this year - introduce it to defensin-molecules. Defensins can be incorporated into your existing skincare regimen and do not conflict or compete with other skincare. Whether it’s CHANEL or Clinique, incorporating DefenAge + Defensins can actually enhance the skincare you already know and love.   Consumer survey says that 93% of consumers who use CHANEL skincare also like the results they see with DefenAge! / Survey 2019, data on file /   “Why do CHANEL users like DefenAge? – this is simple – DefenAge’s defensins multiply the effect of other skincare. …Ironically, DefenAge skin care has no competition on the skincare market because it enhances any other skin care brands. Much like laser treatments and microneedling, the topical application of defensins causes our body to message ‘preserved,’ healthy cells to create visibly new skin. I recommend the BioSerum to my patients to activate their “skin’s memory”, triggering skin to look younger, twice a day – in the morning and evening by applying just one drop of DefenAge BioSerum over the moisturizer of their choice,” -Board-certified dermatologist Natalie M. Curcio, M.D., M.P.H.   Check with us, what other skincare than CHANEL can be combined with DefenAge's defensins for more glowing skin.       Opinions and Stories   Healthy, Simple, and Safe Skincare Routines with Defensins from Supermodel Veronica Webb by Veronica Webb, supermodel mom and influencer Aging powerfully is as much about your attitude as it is about the skincare products you use. Veronica Webb, supermodel, mom, influencer, and beauty writer talks dermatologist recommended anti-aging clean beauty serums, moisturizers, and cleansers. Veronica shares her take simple safe and healthy confidence-boosting skincare routines that make a daily difference. Read more ...   How Effective Is Combining Products From Different Skincare Lines? by Eliza Cabana, aesthetic and skin rejuvenation guru Don’t want to give up your Chanel (or other) skincare product for something new? With DefenAge, you don’t have to! One expert explains how you can combine your favorite products with the DefenAge line to get all the benefits of both. Read more ...   The Secret to Effective 'Anti-Aging' by Eliza Cabana, aesthetic and skin rejuvenation guru Who doesn’t love a good anti-aging cream? But will it actually turn back the clock for your skin? One expert shares her perspective on the “anti-aging” misnomer as well as tips for what steps you can take to get the most out of your skincare routine. Read more...   Introduce Your Skin to the Benefits of DefenAge’s 8-in-1 BioSerum This Year DefenAge’s 8-in-1 BioSerum may be lightweight, but it packs more Defensin molecules than any of DefenAge’s other products. Age-Repair Defensins wake up dormant cells to make brand-new, healthy cells. The result is skin that looks brighter, smoother, and firmer. If you don’t want to use retinol, try the dermatologist recommended skin care from DefenAge, including 8-in-1 BioSerum. Age-Repair Defensins are just as effective as retinol. Read more...   How to Get the Best Results From Your Anti-Aging Skin Care Products The best anti aging skin care products will help your skin look brighter, smoother, plumper, and reduce the appearance of wrinkles. But if you want to truly maximize the product’s effectiveness, there are several things to keep in mind. Using skin care products that address signs of aging is a commitment, but it’s worth it when you start seeing results. Read more...   DefenAge’s Anti-Aging Serum: A Spring Skin Care Must-Have The 8-in-1 BioSerum, anti-aging serum, from DefenAge is a best-selling product with the highest concentration of Age-Repair Defensins. Defensins are molecules that prompt dormant cells to make brand-new, healthy skin cells. DefenAge is the only brand to use Age-Repair Defensins, a proprietary ingredient. The result is new skin cells that look younger and healthier. DefenAge’s products don’t merely cover signs of visible aging.

24/7 BARRIER BALANCE ANTI-AGING CREAM

Intense hydrating cream infused with Age-Repair Defensins®, multi-action barrier balancing ingredients and skin brightening skincare actives work together to regenerate and rejuvenate the appearance of skin.    •  Innovative formula helps replenish and balance the skin's natural barrier. •  Revives radiance and improves overall tone and texture for remarkably smooth, even skin. •  With regular use, skin looks brighter and feels firmer.   Made in the U.S.A.

3D EYE RADIANCE CREAM

Technology-loaded anti-aging skincare treatment designed to address challenging cosmetic concerns for the skin around the eyes. Infused with breakthrough Age-Repair Defensins®.  Read a dermatologist’s opinion and recommendations ►   •  Visibly lifts, firms, and smooths the upper eyelids. •  Fades dark circles and diminishes the appearance of skin discoloration. •  Reduces puffiness and "bumps" under the eyes. •  Fades the appearance ofcrow’s feet and fine lines around the eyes. •  Safe to apply to both the upper lid and under the eyes. •  Can be used together with a retinol, if retinol is tolerated. Effective as a retinol alternative for retinol-sensitive skin. •  Perfect as a standalone eye skincare; also recommended by dermatologists as a complement to aesthetic treatments, including skin resurfacing, microneedling, fractional lasers, and for post neuromodulator- and filler-injections around the eyes and upper face. •  Free from irritants, suitable for all skin types, safe for contact lens wearers.  •  Metal applicator with Cooling Tip Technology allows a clean, gentle, finger-free application, providing soothing benefits. •  Award Winning Eye Cream - two awards: Named 2020 The Best Eye Cream for Dark Circles by NewBeauty Magazine and 2019 Eye Product of the Year by Beauty Independent Innovation Award.   Made in the U.S.A.     DefenAge® Beauty Brand An award-winning beauty brand, DefenAge Skincare is endorsed by the world’s leading dermatologists. DefenAge’s professional-grade, age-repairing products are formulated to globally improve the visual appearance of aging skin for both women and men. DefenAge’s proprietary use of defensin-molecules is the signature difference. The company has also won three prestigious beauty awards for its innovations. DefenAge’s products can help improve visible skin density, the look of wrinkles and dark spots, and boost collagen production.     Opinions and Stories   Five Reasons Why The Skin Around Our Eyes Ages and How To Prevent It by Wendy Lewis, award-winning writer A few factors cause visible changes on the skin around the eyes and detractes a youthful appearance, including wrinkles, loss of skin elasticity, "bumps under eyes," and dark circles around eyes. Dermatologist, Jessica Weiser, MD explains, “One main reason the eye area is prone to premature aging is because this skin is significantly thinner than skin elsewhere on the face and body.”     Accelerate Anti-Aging With The Award-Winning Eye Radiance Cream From DefenAge Wake up dormant skin cells to make brand-new, healthy cells with the eye cream from DefenAge, a premium skin care brand that formulates using proprietary Age-Repair Defensins. Scientifically-advanced skin rejuvenation products for the skin around the eyes from DefenAge include an award-winning eye cream and face serum, plus a fine cleanser.

10 LUXE HAND AND BODY CREAM

If you ever mused aloud, "I wish I could slather my entire body with DefenAge," then the new 10 Luxe Hand & Body Cream answers your call. According to key opinion leaders in aesthetic medicine, our new regenerative anti-aging lotion for crepey skin delivers much more than a product that simply feels soft to the touch. Expert opinions ►   •  Visibly enhances firmness and cosmetic elasticity. •  Improves the appearance of crepey skin. •  Refines the surface skin texture. •  Provides both instant and long-lasting hydration including in dry climates. Boosts natural moisture retention. Skin feels firmer and plumper immediately. •  Relieves the feeling of dryness and itching. •  Balances the skin’s barrier function. •  Promotes the skin’s natural hyaluronic acid, laminin, and elastin. •  Improves visible skin thickness. •  Reverses signs of skin aging, premature aging, and sun damage. •  Effective on elbows and knees; visibly revives their smooth texture and revitalizes softness. •  For use as an anti-aging hand lotion, it smooths and softens the skin on the hands. •  Keeps skin glowing all over the body. •  Beneficial in combination with body contouring procedures to improve visible skin firmness and overall skin quality. •  Recommended in pairing with skin rejuvenation treatments (i.e., peels, IPL, microneedling, and lasers) to amplify results in the reduction of the look of pigmentation, sun damage, crepeness, and mild skin laxity.   Why it’s different • Contains defensin-molecules. Encompasses 7-year knowledge and research collected on the clinical performance of defensins compared to retinol anti-aging tightening lotions. • Provides anti-aging benefits on a global scale. • Promotes new ‘younger’ skin. • Effective on both the hands and body. • Fast acting: first results from ‘immediate’ to 1 week, full range of results in 6 weeks. • Non-irritating retinol alternative. Delivers retinol-like results. • Rich luxurious texture, elegant feel, clean smell of natural ingredients. Fragrance free. • Absorbs quickly, not sticky or tacky, and does not leave a greasy feeling. • Four-pillar formulation strategy: ◦ Global anti-aging (defensin-molecules) ◦ Natural moisturization & comprehensive barrier repair (Ophiopogon japonicus root extract, Sinorhizobium meliloti ferment) ◦ Soothing & calming via anti-inflammation (sea whip, panthenol) ◦ DefenAge’s hero blend of ingredients proven to be well-paired with defensins (including niacinamide and squalane) • Advanced clean beauty standards, No PEGs or animal- or human-derived ingredients. • Developed in response to demand by the medical community, aesthetic service providers, and customers.   Made in the U.S.A.     PRESS RELEASE DefenAge Unveils First-Ever Body Cream Containing Defensin-Molecules Carlsbad, CA – September 01, 2021 – DefenAge® Skincare, manufacturer and distributor of revolutionary, evidence-based, anti-aging products, today announces the launch of its long-awaited 10 Luxe Hand & Body Cream, developed in response to the demand by aesthetic medical professionals and customers. Infused with DefenAge’s famed and exclusive defensin-molecules, the new hand and body cream bathes skin in the most powerful age-reversal skincare technology on the market. Read more ►

12-FACTOR REVITALIZING LIP ENHANCER

12-Factor Revitalizing Lip Enhancer Details Step into the future of lip ...