NexGard 4-10 lbs Dogs, 3 Month, Flea & Tick Treatment
How to Order Prescriptions Description NexGard, which has demonstrated excellent efficacy at low dose, is the first and only soft beef-flavored chew approved to kill both fleas and ticks. It contains the novel active ingredient afoxolaner, an isoxazoline based compound with a new and distinct mode of action. Benefits Its irresistible beef flavor makes it easy to give It kills fleas fast, before they lay eggs, preventing infestation And, it kills American dog Ticks, Lone star ticks, Black-legged (deer) ticks Indications NexGard kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of Black-legged tick (Ixodes scapularis), American Dog tick (Dermacentor variabilis), Lone Star tick (Amblyomma americanum), and Brown dog tick (Rhipicephalus sanguineus) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for one month. How It Works NexGard contains a brand new ingredient not used in any other flea and tick protection. Afoxolaner, the ingredient in NexGard, is rapidly absorbed into your pet's bloodstream where a good concentration makes your pet's blood toxic to insects without affecting your pet's health. The Afoxolaner is metabolized gradually to ensure that it remains in your pet's bloodstream in the appropriate concentration for a full 30 days. When a flea or tick attempts to feast on your pet's blood, Afoxolaner acts on their Central Nervous System by impeding an important neurotransmitter, which causes instantaneous death. This means your pet receives amazing protection in one tasty morsel! NexGard is a prescription-only medication, so talk to your veterinarian about using it for your pet. Ingredients NexGard Chewables for Small Dogs 4-10 lbs Active Ingredient (per tablet) Amount Afoxolaner 11.3 mg NexGard Chewables - For Medium Dogs 10.1-24 lbs Active Ingredient (per tablet) Amount Afoxolaner 28.3 mg NexGard Chewables - For Large Dogs 24.1-60 lbs Active Ingredient (per tablet) Amount Afoxolaner 68 mg NexGard Chewables - For Extra Large Dogs 60-121 lbs Active Ingredient (per tablet) Amount Afoxolaner 136 mg Directions NexGard is given orally once a month, at the minimum dosage of 1.14 mg/lb (2.5 mg/kg). Dosing Schedule Body Weight Afoxolaner Per Chewable (mg) Chewables Administered 4.0 to 10.0 lbs 11.3 1 Orange 10.1 to 24.0 lbs 28.3 1 Blue 24.1 to 60.0 lbs 68 1 Purple 60.1 to 121.0 lbs 136 1 Red Over 121.0 lbs Administer the appropriate combination of chewables NexGard can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NexGard and resume a monthly dosing schedule. Flea Treatment and Prevention Treatment with NexGard may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with NexGard should continue the entire year without interruption. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product. Tick Treatment and Control Treatment with NexGard may begin at any time of the year (see Effectiveness). Contraindications There are no known contraindications for the use of NexGard. Warnings Not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately. Precautions The safe use of NexGard in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures (see Adverse Reactions). Adverse Reactions In a well-controlled US field study, which included a total of 333 households and 615 treated dogs (415 administered afoxolaner; 200 administered active control), no serious adverse reactions were observed with NexGard. Over the 90-day study period, all observations of potential adverse reactions were recorded. The most frequent reactions reported at an incidence of > 1% within any of the three months of observations are presented in the following table. The most frequently reported adverse reaction was vomiting. The occurrence of vomiting was generally self-limiting and of short duration and tended to decrease with subsequent doses in both groups. Five treated dogs experienced anorexia during the study, and two of those dogs experienced anorexia with the first dose but not subsequent doses. Effectiveness In a well-controlled laboratory study, NexGard began to kill fleas four hours after initial administration and demonstrated >99% effectiveness at eight hours. In a separate well-controlled laboratory study, NexGard demonstrated 100% effectiveness against adult fleas 24 hours post-infestation for 35 days, and was ≥93% effective at 12 hours post-infestation through Day 21, and on Day 35. On Day 28, NexGard was 81.1% effective 12 hours post-infestation. Dogs in both the treated and control groups that were infested with fleas on Day -1 generated flea eggs at 12- and 24-hours post-treatment (0-11 eggs and 1-17 eggs in the NexGard treated dogs, and 4-90 eggs and 0-118 eggs in the control dogs, at 12- and 24-hours, respectively). At subsequent evaluations post-infestation, fleas from dogs in the treated group were essentially unable to produce any eggs (0-1 eggs) while fleas from dogs in the control group continued to produce eggs (1-141 eggs). In a 90-day US field study conducted in households with existing flea infestations of varying severity, the effectiveness of NexGard against fleas on the Day 30, 60 and 90 visits compared with baseline was 98.0%, 99.7%, and 99.9%, respectively. Collectively, the data from the three studies (two laboratory and one field) demonstrate that NexGard kills fleas before they can lay eggs, thus preventing subsequent flea infestations after the start of treatment of existing flea infestations. In well-controlled laboratory studies, NexGard demonstrated >97% effectiveness against Dermacentor variabilis, >94% effectiveness against Ixodes scapularis, and >93% effectiveness against Rhipicephalus sanguineus, 48 hours post-infestation for 30 days. At 72 hours post-infestation, NexGard demonstrated >97% effectiveness against Amblyomma americanum for 30 days.
Heartland Vet Supply
